学术报告 - Epigenetics and Epigenomics in Cancers

报告题目:    Epigenetics and Epigenomics in Cancers  
 
报告人:      Fran?ois Fuks Ph.D.
              Professor of ULB, Faculty of Medicine.
              Director of the Laboratory of Cancer Epigenetics
              Director of the ULB Cancer Research Cancer (U-CRC)  
          Faculty of Medicine, Free University of Brussels, Belgium.       
    
主持人:    杨运桂 研究员
 
时间:      20161024 (星期一)上午 10:0011:30   
 
地点:      中国科学院北京基因组研究所一层报告厅 
 
报告摘要
    Since chemical modifications of DNA or histones are reversible processes, there is potentially a huge benefit in modulating such modifications for the treatment of human cancers using pharmacological drugs. To achieve such anti-cancer therapy, it is essential to decipher the molecular mechanisms underlying epigenetic and epigenomic perturbations in tumours. We will present our recent efforts, using our epigenomic plateform EPICS (www.epics.ulb.be), to better understand and map epigenetic alterations in cancers, including DNA methylation and hydroxymethylation.We will also discuss about our very recent work on an emerging realm of biological regulation, termed RNA epigeneticsWe will present our ongoing attempts to decipher the roles of a novel RNA modification: RNA hydroxymethylation.
 
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